Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 124
interventional 86
Observational 30
Registry 8

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 24
Drug 14
Drug|placebo 11
Procedure 10
Other 7
Biological|placebo 4
Biological 3
Device|Other 2
Diagnostic Test 2
Behavioral|Device 1
Biological|Drug 1
Device|Drug 1
Device|Drug|Procedure 1
Device|Procedure 1
Drug|Other 1
Drug|Procedure 1
Genetic 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 27
Germany 6
France 5
United Kingdom 5
United States|Canada 5
Spain 4
Canada 3
Brazil 2
India 2
Italy 2
Japan 2
Netherlands 2
Romania 2
Sweden 2
Argentina 1
Australia|New Zealand|United Kingdom 1
Austria|United States|Belgium|Canada|Czech Republic|Denmark|France|Germany|Hungary|Ireland|Italy|Norway|Spain|Sweden|United Kingdom 1
Czechia|Denmark|Germany|Switzerland 1
Denmark 1
Denmark|Germany|Italy 1
France|Germany|Netherlands|Switzerland 1
Ireland 1
Israel 1
Korea, Republic of 1
Mexico 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Chile|Czechia|Denmark|Estonia|Finland|France|Germany|Hong Kong|Hungary|India|Israel|Italy|Latvia|Lithuania|Mexico|Netherlands|Norway|Poland|Portugal|Puerto Rico|Romania|Russian Federation|Slovakia|South Africa|Spain|Sweden|Switzerland|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|China|Czechia|Denmark|France|Germany|Italy|Japan|Netherlands|Poland|Singapore|Spain|Switzerland|United Kingdom 1
United States|Austria|Belgium|Canada|Czechia|France|Germany|Israel|Italy|Spain|Switzerland 1
United States|Austria|Canada|Spain|Colombia|Czechia|Denmark|Germany|India|Israel|Italy|Japan|Malaysia|Netherlands|Saudi Arabia|Slovenia|South Africa|Sweden|Switzerland|United Arab Emirates|United Kingdom 1
United States|Germany|Poland 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 47
2 10
4 1
5 4
7 2
10 3
11 2
16 1
17 1
18 1
19 1
32 1
34 1
36 1
39 1
40 1
47 1
54 1
65 1
67 1
71 1
83 1
122 1
754 1

Phase

Phase Study_Count
N/A 41
Phase 2 13
Phase 4 11
Phase 3 10
Phase 1 7
Phase 1/Phase 2 2
Phase 2/Phase 3 2

Number of Arms

Number_of_Arms Count_of_Studies
1 24
2 47
3 4
4 4
NA 7

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 16.000 6.00000 10.00 16.0000 66 7.00 6.00000
1st Qu. 49.750 10.00000 23.75 49.0000 81 20.25 10.00000
Median 98.500 20.00000 37.50 92.0000 96 50.00 63.00000
Mean 370.875 30.71429 37.50 119.5385 96 1388.10 76.63636
3rd Qu. 318.500 35.50000 51.25 162.0000 111 345.00 118.50000
Max. 2770.000 98.00000 65.00 294.0000 126 10917.00 252.00000

Trial Group Type

group_type Group_Count
Experimental 68
Active Comparator 37
Placebo Comparator 17
No Intervention 11
Other 10
NA 7
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 51
Single Group Assignment 28
Crossover Assignment 6
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 61
Diagnostic 11
Prevention 6
Other 4
Basic Science 2
Screening 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 4
France 3
Canada 2
China 2
Italy 2
Netherlands 2
Sweden 2
United Kingdom 2
Austria 1
Belgium 1
Brazil 1
Denmark 1
Germany 1
Greece 1
Hungary 1
NA 1
Spain 1
United States|Canada|Puerto Rico 1
United States|Israel 1

Sites per Study

Site_count Study_Count
1 23
2 2
3 1
7 1
14 1
90 1
144 1

Enrollment Metrics

Measure Observational
Min 3.000
1st Qu 60.000
Median 160.000
Mean 1644.379
3rd Qu 450.000
Max 34810.000

Observation Model

observational_model Study_Count
Cohort 22
Case-Only 3
Case-Control 1
Case Control 1
Defined Population 1
Other 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 26
Cross-Sectional 1
Longitudinal, Retrospective/Prospective 1
Retrospective 1
NA 1

Registries

Studies by Country

Country Study_Count
Italy 2
Austria|Czechia|Denmark|Germany|Israel|Italy|Kazakhstan|Netherlands|Poland|Singapore|United Kingdom 1
Croatia 1
France 1
Germany 1
NA 1
United States 1

Sites per Study

Site_count Study_Count
1 6
2 1
26 1

Enrollment Metrics

Measure Registries
Min 50.000
1st Qu 59.000
Median 320.000
Mean 452.125
3rd Qu 739.000
Max 1163.000

Registry Model

observational_model Study_Count
Cohort 3
Case-Only 2
Other 2
Case-Crossover 1

Time Perspective

time_perspective Study_Count
Prospective 6
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
1 Month 2
1 Year 1
10 Years 1
2 Years 1
3 Months 1
376 Days 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04222764 Evaluation of the Right Ventricular Systolic Function Using Real-time Three-dimensional Echocardiography in Intensive Care Unit Patients https://ClinicalTrials.gov/show/NCT04222764 Recruiting University Hospital, Limoges 2023-12-03
NCT03301571 Right Ventricular Echocardiography in caRdiac SurgEry https://ClinicalTrials.gov/show/NCT03301571 Completed Rigshospitalet, Denmark 2017-10-05
NCT03257436 Strategic Management to Improve CRT Using Multi-Site Pacing Post Approval Study (Reference # C1918) https://ClinicalTrials.gov/show/NCT03257436 Active, not recruiting Boston Scientific Corporation 2020-06-30
NCT03232736 InterventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With LVAD’s https://ClinicalTrials.gov/show/NCT03232736 Recruiting University of Colorado, Denver 2020-08-30
NCT03202641 Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients https://ClinicalTrials.gov/show/NCT03202641 Recruiting Massachusetts General Hospital 2020-04-01
NCT02962921 Insulin Effects on Cardiac Function in Patients With Diabetes Mellitus https://ClinicalTrials.gov/show/NCT02962921 Completed Rambam Health Care Campus 2003-05-31
NCT02931240 BioVentrix Revivent TCâ„¢ System Clinical Study https://ClinicalTrials.gov/show/NCT02931240 Recruiting BioVentrix 2022-03-01
NCT02757976 Resynchronization for Ambulatory Heart Failure Trial - LV Endocardial https://ClinicalTrials.gov/show/NCT02757976 Recruiting Lawson Health Research Institute 2022-01-31
NCT02687932 Pharmacological Reduction of Functional, Ischemic Mitral REgurgitation https://ClinicalTrials.gov/show/NCT02687932 Completed Asan Medical Center 2018-01-02
NCT02668419 Electrical Stimulation Improves Exercise Tolerance in Patients With Advanced Heart Failure on Continuous Dobutamine Use https://ClinicalTrials.gov/show/NCT02668419 Completed Federal University of São Paulo 2014-12-31
NCT03403868 Right Ventricular Haemodynamic Evaluation and Response to Treatment https://ClinicalTrials.gov/show/NCT03403868 Recruiting University of Giessen 2018-12-01
NCT02543294 REcovery of Left Ventricular Dysfunction in CAncer Patients (RECAP Trial) https://ClinicalTrials.gov/show/NCT02543294 Completed M.D. Anderson Cancer Center 2017-09-10
NCT02530788 High-dose Selenium Supplementation in Patients With Left Ventricular Assist https://ClinicalTrials.gov/show/NCT02530788 Completed RWTH Aachen University 2017-07-31
NCT02452515 A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction https://ClinicalTrials.gov/show/NCT02452515 Completed Bayer 2016-01-31
NCT02362646 Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients https://ClinicalTrials.gov/show/NCT02362646 Completed Icahn School of Medicine at Mount Sinai 2018-08-10
NCT02354989 Rate RESPONSIVe Pacing in Patients With Permanent AF Underwent AV Node ABLation and bivEntricular Pacing (RESPONSIBLE) https://ClinicalTrials.gov/show/NCT02354989 Completed Azienda Ospedaliera Cardinale G. Panico 2015-02-28
NCT02133352 Study of Ranolazine in the Treatment of Pulmonary Hypertension Associated With Diastolic Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT02133352 Completed Boston University 2013-05-31
NCT02070991 Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT02070991 Completed Actelion 2015-11-01
NCT01294527 Wireless Stimulation Endocardially for Cardiac Resynchronization Therapy https://ClinicalTrials.gov/show/NCT01294527 Completed EBR Systems, Inc. 2012-04-30
NCT02013674 The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis STudy (The TRIDENT Study) https://ClinicalTrials.gov/show/NCT02013674 Completed University of Miami 2017-03-02
NCT02013037 The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation https://ClinicalTrials.gov/show/NCT02013037 Active, not recruiting Cedars-Sinai Medical Center 2019-08-30
NCT01995552 IdeNtifying High riSk Patients Post Myocardial Infarction With REduced Left Ventricular Function Using External Loop Recorders (INSPIRE-ELR Study) https://ClinicalTrials.gov/show/NCT01995552 Completed Medtronic BRC 2016-02-20
NCT01936649 Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView. https://ClinicalTrials.gov/show/NCT01936649 Completed GE Healthcare 2014-02-28
NCT01920048 Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure https://ClinicalTrials.gov/show/NCT01920048 Active, not recruiting King’s College London 2020-03-31
NCT01842243 Effect of Septal Versus Apical Pacing- a Comparative Study Using Cardiac MRI https://ClinicalTrials.gov/show/NCT01842243 Completed Manchester University NHS Foundation Trust 2015-12-31
NCT01800292 Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH. https://ClinicalTrials.gov/show/NCT01800292 Completed University of Arizona 2013-12-31
NCT01780727 Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery https://ClinicalTrials.gov/show/NCT01780727 Completed University of Nebraska 2018-05-31
NCT01652248 Pacemaker Upgrade to Cardiac Resynchronisation Therapy in Patients With Left Ventricular Dysfunction Dependant Upon Right Ventricular Pacing https://ClinicalTrials.gov/show/NCT01652248 Completed University of Leeds 2011-12-31
NCT01446965 Vest Prevention of Early Sudden Death Trial and VEST Registry https://ClinicalTrials.gov/show/NCT01446965 Completed University of California, San Francisco 2019-05-31
NCT01442129 The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation https://ClinicalTrials.gov/show/NCT01442129 Completed Icahn School of Medicine at Mount Sinai 2013-03-31
NCT04194632 Right Ventricular Pacing in Pulmonary Arterial Hypertension https://ClinicalTrials.gov/show/NCT04194632 Recruiting University of California, San Francisco 2021-12-05
NCT04111133 Ivabradine in Cirrhotic Cardiomyopathy https://ClinicalTrials.gov/show/NCT04111133 Recruiting Postgraduate Institute of Medical Education and Research 2021-10-31
NCT04034940 Correlations Between Oxidative Stress Biomarkers, h-FABP and Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Undergoing Primary PCI https://ClinicalTrials.gov/show/NCT04034940 Recruiting Grigore T. Popa University of Medicine and Pharmacy 2020-07-31
NCT03887286 Focused Cardiac Ultrasound https://ClinicalTrials.gov/show/NCT03887286 Completed University of Miami 2019-05-30
NCT03806582 Effect of a Higher Blood-pressure on Right Ventricular Function https://ClinicalTrials.gov/show/NCT03806582 Completed Medical Centre Leeuwarden 2020-05-15
NCT03799133 Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac Surgery https://ClinicalTrials.gov/show/NCT03799133 Completed Critical Perfusion Inc. 2019-12-28
NCT03746938 First in Humans to Evaluate Collagen Patches With Stem Cells in Patients With Ischemic Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT03746938 Recruiting Viscofan 2020-10-30
NCT03715998 Firibastat or Ramipril After Acute Myocardial Infarction for Prevention of Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT03715998 Recruiting Quantum Genomics SA 2020-09-01
NCT03627585 Reprogramming to Prevent Progressive Pacemaker-induced Remodelling https://ClinicalTrials.gov/show/NCT03627585 Completed University of Leeds 2019-01-06
NCT03581877 Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE https://ClinicalTrials.gov/show/NCT03581877 Recruiting Northwell Health 2021-12-31
NCT01258387 Single Ascending Doses of GGF2 in Patients With Left Ventricular Dysfunction and Symptomatic Heart Failure https://ClinicalTrials.gov/show/NCT01258387 Completed Acorda Therapeutics 2012-12-31
NCT02022514 Intracoronary Infusion of Mononuclear Cells Autologous Bone Marrow in Patients With Chronic Coronary Occlusion and Ventricular Dysfunction, Previously Revascularized. https://ClinicalTrials.gov/show/NCT02022514 Recruiting Andalusian Network for Design and Translation of Advanced Therapies 2021-11-30
NCT01128790 Pilot Study of Remote Ischemic Preconditioning in Heart Failure https://ClinicalTrials.gov/show/NCT01128790 Completed University Health Network, Toronto 2011-06-30
NCT01110824 Prevention of Left Ventricular Dysfunction During Chemotherapy https://ClinicalTrials.gov/show/NCT01110824 Completed Hospital Clinic of Barcelona 2011-12-31
NCT01093001 Tricuspid Regurgitation Study https://ClinicalTrials.gov/show/NCT01093001 Completed Mayo Clinic 2015-09-30
NCT01065454 A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction https://ClinicalTrials.gov/show/NCT01065454 Active, not recruiting Bayer 2012-06-06
NCT00998218 Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction https://ClinicalTrials.gov/show/NCT00998218 Completed Aspirus Heart and Vascular Institute-Research and Education 2010-12-31
NCT00982397 Safety and Clinical Performance of the Protecta ICD and CRT-D https://ClinicalTrials.gov/show/NCT00982397 Completed Medtronic Cardiac Rhythm and Heart Failure 2013-09-30
NCT00981006 AutoLogous Human CArdiac-Derived Stem Cell to Treat Ischemic cArdiomyopathy (ALCADIA) https://ClinicalTrials.gov/show/NCT00981006 Completed Kyoto Prefectural University of Medicine 2013-03-31
NCT00942487 Effects of Nebivolol on Subclinical Left Ventricular dySfunction: A Comparative Study Against Metoprolol https://ClinicalTrials.gov/show/NCT00942487 Completed Berlin-Chemie Menarini 2008-12-31
NCT00938847 Bone Marrow Derived Mononuclear Cells For Myocardial Regeneration https://ClinicalTrials.gov/show/NCT00938847 Completed Asklepios proresearch 2007-10-31
NCT00921960 St. Vincent’s Screening To Prevent Heart Failure Study https://ClinicalTrials.gov/show/NCT00921960 Completed St Vincent’s University Hospital, Ireland 2017-12-31
NCT00919373 Substrate Modification in Stable Ventricular Tachycardia in Addition to Implantable Cardioverter Defibrillator (ICD) Therapy https://ClinicalTrials.gov/show/NCT00919373 Completed Abbott Medical Devices 2006-01-31
NCT00893360 CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction https://ClinicalTrials.gov/show/NCT00893360 Completed Cedars-Sinai Medical Center 2011-08-31
NCT01673230 Hemodynamic Indices Predictive of a Beneficial Response to Fluid Expansion in Case of Hemodynamic Failure After Cardiac Surgery With Altered Preoperative Ejection Fraction (LVEF≤45%) https://ClinicalTrials.gov/show/NCT01673230 Completed Rennes University Hospital 2015-12-31
NCT00824005 Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) https://ClinicalTrials.gov/show/NCT00824005 Completed The University of Texas Health Science Center, Houston 2011-11-30
NCT01571037 Inhaled Milrinone Use in Patients Receiving HeartMate II LVAD: A Pilot Study https://ClinicalTrials.gov/show/NCT01571037 Completed University of Nebraska 2013-02-28
NCT01959828 Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery https://ClinicalTrials.gov/show/NCT01959828 Completed Mallinckrodt 2014-03-31
NCT00781508 Effects of Viagra on Heart Function in Patients With Heart Failure https://ClinicalTrials.gov/show/NCT00781508 Completed MetroHealth Medical Center 2009-09-30
NCT00768066 The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT) https://ClinicalTrials.gov/show/NCT00768066 Completed University of Miami 2012-08-31
NCT00748982 Investigate the Effect of AZD1305 on Patients With Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT00748982 Completed AstraZeneca 2009-07-31
NCT00684060 Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study) https://ClinicalTrials.gov/show/NCT00684060 Completed The University of Texas Health Science Center, Houston 2011-08-31
NCT00684021 Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study) https://ClinicalTrials.gov/show/NCT00684021 Completed The University of Texas Health Science Center, Houston 2012-05-31
NCT00557934 Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot https://ClinicalTrials.gov/show/NCT00557934 Completed University Hospital Tuebingen 2008-09-30
NCT00551681 Effects of Left Ventricular Pacing Optimilization on Cardiac Perfusion, Contractile Force, and Clinical Performance in Patients With Ventricular Dysfunction and Heart Failure https://ClinicalTrials.gov/show/NCT00551681 Completed R&D Cardiologie 2015-02-28
NCT00526162 ConsultaTM CRT-D Clinical Evaluation Study https://ClinicalTrials.gov/show/NCT00526162 Completed Medtronic Bakken Research Center 2008-01-31
NCT00507468 Autologous Bone Marrow Transplanted Via Transendocardial Catheter to Chronic Myocardial Infarct Border Zone https://ClinicalTrials.gov/show/NCT00507468 Completed BioCardia, Inc. 2009-03-31
NCT00461734 PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing https://ClinicalTrials.gov/show/NCT00461734 Completed Medtronic Cardiac Rhythm and Heart Failure 2013-10-31
NCT01076920 Mesenchymal Stem Cells and Myocardial Ischemia https://ClinicalTrials.gov/show/NCT01076920 Completed University Hospital, Toulouse 2014-02-28
NCT00391846 Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone https://ClinicalTrials.gov/show/NCT00391846 Completed AstraZeneca 2009-01-31
NCT00385242 PET and Recovery Following Revascularization (PARR 2) https://ClinicalTrials.gov/show/NCT00385242 Completed Ottawa Heart Institute Research Corporation 2006-06-30
NCT00370643 Glucose Control in Open Heart Surgery https://ClinicalTrials.gov/show/NCT00370643 Completed University of Sao Paulo NA
NCT00358215 RED-HFâ„¢ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial https://ClinicalTrials.gov/show/NCT00358215 Completed Amgen 2012-10-11
NCT00321295 Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery https://ClinicalTrials.gov/show/NCT00321295 Completed William Beaumont Hospitals 2006-10-31
NCT00284830 SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction https://ClinicalTrials.gov/show/NCT00284830 Completed Medtronic Cardiac Rhythm and Heart Failure 2006-12-31
NCT00271154 REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE) https://ClinicalTrials.gov/show/NCT00271154 Completed Medtronic Cardiac Rhythm and Heart Failure 2007-10-31
NCT00259038 Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure https://ClinicalTrials.gov/show/NCT00259038 Completed Daiichi Sankyo, Inc. 2006-02-28
NCT00187278 Biopace Study: Biventricular Pacing for Atrioventricular Block to Prevent Cardiac Desynchronization https://ClinicalTrials.gov/show/NCT00187278 Completed Abbott Medical Devices 2014-05-31
NCT00187252 Mascot Study: Management of Atrial Fibrillation (AF) Suppression in AF-Heart Failure (HF) COmorbidity Therapy https://ClinicalTrials.gov/show/NCT00187252 Completed Abbott Medical Devices 2008-06-30
NCT00187213 B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients https://ClinicalTrials.gov/show/NCT00187213 Completed Abbott Medical Devices 2007-07-31
NCT00170326 Progressive Ventricular Dysfunction Prevention in Pacemaker Patients https://ClinicalTrials.gov/show/NCT00170326 Completed Medtronic Bakken Research Center 2009-03-31
NCT00143507 The BEAUTIFUL Study: Effects of Ivabradine in Patients With Stable Coronary Artery Disease and Left Ventricular Systolic Dysfunction https://ClinicalTrials.gov/show/NCT00143507 Completed Servier 2008-02-29
NCT00121485 Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy https://ClinicalTrials.gov/show/NCT00121485 Completed Abbott Medical Devices 2009-06-30
NCT00121472 Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation https://ClinicalTrials.gov/show/NCT00121472 Completed Abbott Medical Devices 2006-11-30
NCT00120276 RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve https://ClinicalTrials.gov/show/NCT00120276 Completed Myocor NA
NCT00112320 Comparison of Two Pulmonary Valve Replacement Methods to Treat Tetralogy of Fallot https://ClinicalTrials.gov/show/NCT00112320 Completed Boston Children’s Hospital 2011-08-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04092855 Right Ventricular Pressure Waveform Monitoring in Cardiac Surgery https://ClinicalTrials.gov/show/NCT04092855 Recruiting Montreal Heart Institute 2020-09-30
NCT03231189 Cardiac MRI in Front Line for the Diagnosis of Coronary Artery Disease as the Etiology of Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT03231189 Recruiting Assistance Publique - Hôpitaux de Paris 2021-12-15
NCT03184727 Pulmonary Vasculature and Right Heart Dysfunction in Chronic Obstructive Pulmonay Disease https://ClinicalTrials.gov/show/NCT03184727 Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital 2020-12-31
NCT03183414 Right Ventricular Dysfunction in Cardiac Surgery Patients https://ClinicalTrials.gov/show/NCT03183414 Completed Medical Centre Leeuwarden 2018-06-20
NCT02972918 Preoperative levosimendán and Hip Fracture https://ClinicalTrials.gov/show/NCT02972918 Completed Hospital Universitario de Canarias 2018-09-30
NCT02956577 Cardiac Function and Microcirculation: Type 2 DIABetes and ECHOcardiographic Changes Over Time https://ClinicalTrials.gov/show/NCT02956577 Completed Svendborg Hospital 2018-09-20
NCT02816047 Austrian Wearable Cardioverter Defibrillator Registry https://ClinicalTrials.gov/show/NCT02816047 Recruiting Medical University of Graz 2020-12-31
NCT02428894 Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation https://ClinicalTrials.gov/show/NCT02428894 Completed University of Colorado, Denver 2017-01-31
NCT02340546 Trajectory Changes of Coronary Sinus Lead Tip and Cardiac Resynchronization Therapy Outcome https://ClinicalTrials.gov/show/NCT02340546 Completed Ospedale Santa Maria delle Croci 2019-01-31
NCT02198781 Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot https://ClinicalTrials.gov/show/NCT02198781 Completed Basildon and Thurrock University Hospitals NHS Foundation Trust 2015-08-31
NCT01971125 Left Ventricular DYsfunction in DiAbetes https://ClinicalTrials.gov/show/NCT01971125 Completed Heart Care Foundation 2009-03-31
NCT01609738 Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum https://ClinicalTrials.gov/show/NCT01609738 Completed Maastricht University Medical Center 2015-02-28
NCT01452165 Peripheral Artery Disease in Vastmanland https://ClinicalTrials.gov/show/NCT01452165 Completed Uppsala University 2011-05-31
NCT01440049 Patient’s Management Receiving Eplerenone Therapy https://ClinicalTrials.gov/show/NCT01440049 Completed Pfizer 2010-12-31
NCT01326624 Study of the Wearable Defibrillator in Heart-Failure Patients https://ClinicalTrials.gov/show/NCT01326624 Completed Zoll Medical Corporation 2017-12-31
NCT04405856 Outcome of Patients Treated With IABP https://ClinicalTrials.gov/show/NCT04405856 Recruiting Nanjing Medical University 2025-12-31
NCT03968601 Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery https://ClinicalTrials.gov/show/NCT03968601 Recruiting University Hospital, Clermont-Ferrand 2022-02-28
NCT03787810 Left Ventricular Dysfunction in Critically Ill Patients https://ClinicalTrials.gov/show/NCT03787810 Completed Sahlgrenska University Hospital, Sweden 2019-02-20
NCT03761654 Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN) https://ClinicalTrials.gov/show/NCT03761654 Recruiting University Hospital, Bordeaux 2020-06-30
NCT03755570 How is COGNItive Function Affected by Cardiac Resynchronisation Therapy? https://ClinicalTrials.gov/show/NCT03755570 Recruiting Royal Cornwall Hospitals Trust 2021-09-23
NCT03438825 PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients https://ClinicalTrials.gov/show/NCT03438825 Completed Semmelweis University Heart and Vascular Center 2018-11-30
NCT01178866 Laboratory Outcome Predictors in Coronary Surgery https://ClinicalTrials.gov/show/NCT01178866 Completed University of Sao Paulo 2008-01-31
NCT01114269 PRE-DETERMINE Cohort Study https://ClinicalTrials.gov/show/NCT01114269 Active, not recruiting Brigham and Women’s Hospital 2021-02-28
NCT01076296 A Post-Marketing Study for On Label Evaluation of the GE Vscan Ultrasound Imaging System https://ClinicalTrials.gov/show/NCT01076296 Completed GE Healthcare 2012-07-31
NCT02147457 Prematurity as Predictor of Children’s Cardiovascular-renal Health https://ClinicalTrials.gov/show/NCT02147457 Completed Universitaire Ziekenhuizen Leuven 2015-12-31
NCT02148991 Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction https://ClinicalTrials.gov/show/NCT02148991 Completed Elpen Pharmaceutical Co. Inc. 2017-01-31
NCT03309852 Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient https://ClinicalTrials.gov/show/NCT03309852 Recruiting University of Manitoba 2020-10-05
NCT00476320 The Use of Myocardial Deformation Imaging https://ClinicalTrials.gov/show/NCT00476320 Completed RWTH Aachen University NA
NCT00359372 Predicting Response to Cardiac Resynchronization Therapy in Heart Failure https://ClinicalTrials.gov/show/NCT00359372 Completed National Institutes of Health Clinical Center (CC) NA
NCT00303979 IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting https://ClinicalTrials.gov/show/NCT00303979 Completed Medtronic Cardiac Rhythm and Heart Failure 2009-08-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03319160 LifeVest Safety and Efficacy in Real Life Settings in France https://ClinicalTrials.gov/show/NCT03319160 Completed Zoll Medical Corporation 2018-09-30
NCT03041337 Right Heart International NETwork During Exercise in Different Clinical Conditions https://ClinicalTrials.gov/show/NCT03041337 Recruiting Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D’Aragona 2020-01-01
NCT02497950 HeartMate 3 ELEVATEâ„¢ https://ClinicalTrials.gov/show/NCT02497950 Active, not recruiting Abbott Medical Devices 2019-02-28
NCT02073942 Cologne Register of Wearable Defibrillator (CRWD) https://ClinicalTrials.gov/show/NCT02073942 Completed University of Cologne 2017-12-31
NCT04397302 Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction https://ClinicalTrials.gov/show/NCT04397302 Completed Italian Society of Cardiology 2020-03-16
NCT04018079 Left Ventricular Dysfunction Post-surgical Patent Ductus Arteriosus Ligation in Children: Predictor Factors Analysis https://ClinicalTrials.gov/show/NCT04018079 Completed South Valley University 2018-06-30
NCT03701997 Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation. https://ClinicalTrials.gov/show/NCT03701997 Enrolling by invitation Berlin Heart, Inc 2021-12-31
NCT03659851 Levosimendan In Patients Undergoing LVAD Implantation https://ClinicalTrials.gov/show/NCT03659851 Recruiting University Hospital Dubrava 2020-12-31